書誌事項
- タイトル別名
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- A case of descending necrotizing mediastinitis arising from odontogenic infection with NSAID-induced gastric ulcer in a very elderly patient
- NSAIDs イカイヨウ オ ヘイハツシタ チョウコウレイシャ ニ オケル シセイ コウカセイ エシセイ ジュウカクエン ノ 1レイ
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We describe an 88-year-old woman with gas-forming submental cellulitis in whom nonsteroidal antiinflammatory drug (NSAID)-induced gastric ulcer led to hemorrhagic shock during treatment of an odontogenic infection. Hemodynamic treatment had to take priority, and intensive treatment for inflammation could not be performed. This apparently led to the development of descending necrotizing mediastinitis. During the six days of hospitalization, she took a total of 6 tablets of loxoprofen sodium (60 mg) and 1 diclofenac sodium suppository (25 mg) for analgesia after treatment.<BR>Retrospectively, if decisive and aggressive treatment for inflammation had been performed earlier after hospitalization, inflammation may have resolved sooner. Our experience reconfirms that the initial treatment of odontogenic infection is extremely important in very elderly patients. Even if NSAIDs are received for a short period of time in small doses, gastrointestinal hemorrhage can occur, as in our patient. Patients at high risk for gastrointestinal ulcer should receive prophylactic treatment with cyclo-oxygenase 2 inhibitors orproton pump inhibitors.Generally, very elderly patients have a high risk of complications because of considerable age-related declines in physical ability and functional reserve of organs. Very cautious treatment is therefore necessary.
収録刊行物
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- 日本口腔外科学会雑誌
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日本口腔外科学会雑誌 54 (9), 541-545, 2008
社団法人 日本口腔外科学会
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詳細情報 詳細情報について
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- CRID
- 1390282681510042752
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- NII論文ID
- 10027089304
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- NII書誌ID
- AN00189163
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- ISSN
- 21861579
- 00215163
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- NDL書誌ID
- 9660774
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可