A case of benign fibrous histiocytoma accompanied by hypoesthesia of the mental region

DOI Web Site 9 References
  • ITO Ko
    Department of Maxillofacial Surgery, Nihon University School of Dentistry at Matsudo Research Institute of Oral Science, Nihon University School of Dentistry at Matsudo
  • FUJIMOTO Yoko
    Department of Maxillofacial Surgery, Nihon University School of Dentistry at Matsudo
  • IWAI Satoshi
    Department of Maxillofacial Surgery, Nihon University School of Dentistry at Matsudo
  • TAKAHASHI Kosuke
    Department of Maxillofacial Surgery, Nihon University School of Dentistry at Matsudo
  • OKADA Hiroyuki
    Research Institute of Oral Science, Nihon University School of Dentistry at Matsudo Department of Histology, Nihon University School of Dentistry at Mastudo
  • KONDOH Toshirou
    Department of Maxillofacial Surgery, Nihon University School of Dentistry at Matsudo Research Institute of Oral Science, Nihon University School of Dentistry at Matsudo

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Other Title
  • オトガイ部知覚鈍麻を合併した良性線維性組織球腫の1例
  • オトガイブ チカク ドンマ オ ガッペイ シタ リョウセイ センイセイ ソシキキュウ シュ ノ 1レイ

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Abstract

Benign fibrous histiocytoma commonly arises in the abdomen and sun-exposed skin and rarely occurs in the oral cavity. A case of benign fibrous histiocytoma arising around the mental foramen is reported. A 23-year-old woman was referred to our hospital because of a painless small mass on the right side of the subgingiva at the first premolar of the mandible, associated with hypoesthesia of the right mental region. The biopsy specimens were pathologically diagnosed to be a non-epithelial tumor, and the tumor was excised under general anesthesia. Microscopically, the tumor consisted of spindle-shaped cells and polygonal cells, and partly formed a storiform pattern. Immunohistochemically, the spindle-shaped cells were positive for vimentin, and the polygonal cells were positive for vimentin and CD68, but both types of cells were negative for NF, S-100, actin, EMA, factor VIII, and CD34. Based on these findings, the tumor was diagnosed to be a benign fibrous histiocytoma. Thirteen weeks after the operation, the hypoesthesia of mental region had completely disappeared. No evidence of recurrence has been noted as of 8 years after surgery.

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