A case of central giant cell granuloma of the hard palate

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  • TACHIBANA Ryusuke
    Second Department of Oral and Maxillofacial Surgery （Department of Oral Medicine）, Tsurumi University School of Dental Medicine
  • SATO Toru
    Second Department of Oral and Maxillofacial Surgery （Department of Oral Medicine）, Tsurumi University School of Dental Medicine
  • KAMIYA Yoko
    Second Department of Oral and Maxillofacial Surgery （Department of Oral Medicine）, Tsurumi University School of Dental Medicine
  • TERADA Chika
    Second Department of Oral and Maxillofacial Surgery （Department of Oral Medicine）, Tsurumi University School of Dental Medicine
  • ASADA Koichi
    Second Department of Oral and Maxillofacial Surgery （Department of Oral Medicine）, Tsurumi University School of Dental Medicine
  • SATOMURA Kazuhito
    Second Department of Oral and Maxillofacial Surgery （Department of Oral Medicine）, Tsurumi University School of Dental Medicine

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Other Title
  • 硬口蓋に発生した中心性巨細胞肉芽腫の1例
  • コウコウガイ ニ ハッセイ シタ チュウシンセイキョサイボウ ニクゲシュ ノ 1レイ

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Abstract

We report the rare case of a central giant cell granuloma of the hard palate. A 30-year-old Japanese woman consulted our clinic because of a swelling of the hard palate. MRI examination showed a well-demarcated homogenous lesion of the hard palate with low signal intensity on T1-weighted images and high signal intensity on STIR. CT revealed a deep crater-like bone defect adjacent to the incisive foramen. Surgical excision was performed with the patient under general anesthesia. Histopathological examination revealed dense proliferation of spindle-shaped cells accompanied by blood capillaries ans multinucleated giant cells. The lesion was diagnosed to be a central giant cell granuloma. There has been no evidence of recurrence as of 17 months after the operation.

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