Sugar Transport Across Erythrocyte Membranes and Osmotic Behavior of Erythrocytes
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- UYESAKA Nobuhiro
- Department of Physiology, Kyoto University Medical School
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- SHINAGAWA Yoshiya
- Department of Physiology, Kyoto University Medical School
Bibliographic Information
- Other Title
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- 赤血球膜の糖輸送と浸透圧挙動
- セッケッキュウ マク ノ トウ ユソウ ト シントウアツ キョドウ
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Abstract
Sugar transport across erythrocyte membrane has been studied by many investigators. Analysis of the Michaelis-Menten kinetics has been applied to the sugar transport since Widdas formulated the carrier mediated transport model. However, many different values of Km and Vmax Were reported due to the different conditions of experiments.<BR>We found striking change in osmotic fragility of human red blood cells in the mixture of NaCl and saccharide solution. The sequence of hemolytic efficiency of saccharides is as follows; D-Xylose_??_L-Arabinose_??_D-Mannose_??_D-Galactose>D-Glucose>2-Deoxy-D-Glucose>[NaCl] _?? D-Ribose>D-Arabinose_??_L-Sorbose_??_L-Fucose>L-Xylose_??_ Xylitol>L-Glucose_??_D-Furctose_??_D-Sorbitol_??_D-Mannitol_??_D-Maltose_??_D-Sucrose. The effect is due to the sugar transport across the membrane, of which kinetics was shown to be a new type. The carrier is apparently a divalent carrier, or the glucose passes through the erythrocyte membrane as a dimer.
Journal
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- Seibutsu Butsuri
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Seibutsu Butsuri 19 (2), 79-92, 1979
The Biophysical Society of Japan General Incorporated Association
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Details 詳細情報について
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- CRID
- 1390282681510711808
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- NII Article ID
- 130000723009
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- NII Book ID
- AN00129693
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- ISSN
- 13474219
- 05824052
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- NDL BIB ID
- 2049423
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed