Functions of Nonmuscle Myosin II Isoforms

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  • TAKAHASHI Masayuki
    Division of Chemistry, Graduate School of Science, Hokkaido University
  • NAKASAWA Takashi
    Division of Chemistry, Graduate School of Science, Hokkaido University
  • SATO Masaaki
    Division of Chemistry, Graduate School of Science, Hokkaido University
  • HIRATA Naoya
    Division of Chemistry, Graduate School of Science, Hokkaido University
  • MITSUHASHI Mariko
    Division of Chemistry, Graduate School of Science, Hokkaido University
  • YAZAWA Michio
    Division of Chemistry, Graduate School of Science, Hokkaido University

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Other Title
  • 非筋細胞ミオシンＩＩアイソフォームの機能
  • 非筋細胞ミオシン2アイソフォームの機能
  • ヒキン サイボウ ミオシン 2 アイソフォーム ノ キノウ

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Description

All vertebrate cells, including muscle cells, contain nonmuscle myosin II which plays a role in a number of cell motility processes. Dynamic filament assembly-disassembly transition of myosin II molecules is particularly important in nonmuscle cells. In this review, we describe our recently proposed molecular mechanism for the filament formation of nonmuscle myosin II. We also discuss the distinct functions of two myosin II isoforms, IIA and IIB, during cell migration.<br>

Journal

  • Seibutsu Butsuri

    Seibutsu Butsuri 46 (1), 15-19, 2006

    The Biophysical Society of Japan General Incorporated Association

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