書誌事項
- タイトル別名
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- Refinement of Amino Acid Substitution Matrix for Detecting Distant Relationships of Proteins
- トオエン タンパクシツ ケンサク ニ テキシタ シンキ アミノサン チカン ギョウレツ
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抄録
Amino acid similarity search methods are fundamental tools for inferring protein structure and function. Optimization of amino acid substitution matrices is indispensable to improve search performance. We explored matrices that are ideal for detecting distantly related proteins in the PCA subspace that represents a set of typical existing matrices, and derived a novel sensitive matrix: MIQS. Test results show that the MIQS detection performance is superior to those of existing matrices and other sequence comparison methods. This refinement of the amino acid substitution matrix might influence many fields of sequence analysis. MIQS is available at http://csas.cbrc.jp/Ssearch/.
収録刊行物
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- 生物物理
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生物物理 55 (3), 133-136, 2015
一般社団法人 日本生物物理学会
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詳細情報 詳細情報について
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- CRID
- 1390282681511225728
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- NII論文ID
- 130005072018
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- NII書誌ID
- AN00129693
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- ISSN
- 13474219
- 05824052
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- NDL書誌ID
- 026554391
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可