シトクロムc翻訳後修飾タンパク質の機能と構造

書誌事項

タイトル別名
  • Structure and Function of Cytochrome c Maturation Proteins
  • シトクロム c ホンヤクゴ シュウショク タンパクシツ ノ キノウ ト コウゾウ

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抄録

c-type cytochromes are electron transfer proteins that are essential for the life of virtually all organisms. They characteristically carry covalently-bound heme via thioether bonds to two cysteines in the protein. In Gram-negative bacteria, biogenesis of c-type cytochrome is conducted by a multiprotein complex system known as the cytochrome c maturation (Ccm) system. This system is consisted of 8 gene products (CcmA-CcmH). CcmE, which is called as a heme chaperon, binds heme and delivers it to apocytochrome c. In this article, I discuss the structure of CcmE and how it works as a heme chaperone protein.<br>

収録刊行物

  • 生物物理

    生物物理 47 (2), 112-117, 2007

    一般社団法人 日本生物物理学会

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