A study on psammoma body mineralization in meningiomas

DOI 29 References
  • WANG Changqiu
    Key Laboratory of Orogenic Belts and Crustal Evolution, MOE, School of Earth and Space Sciences, Peking University
  • YANG Ruochen
    Key Laboratory of Orogenic Belts and Crustal Evolution, MOE, School of Earth and Space Sciences, Peking University China Minerals Corporation
  • LI Yan
    Key Laboratory of Orogenic Belts and Crustal Evolution, MOE, School of Earth and Space Sciences, Peking University
  • XIONG Cuie
    Key Laboratory of Orogenic Belts and Crustal Evolution, MOE, School of Earth and Space Sciences, Peking University
  • ZHAO Wenwen
    Key Laboratory of Orogenic Belts and Crustal Evolution, MOE, School of Earth and Space Sciences, Peking University
  • LIU Jianying
    Pathology Department in School of Basic Medical Science, Peking University Health Science Center
  • ZHANG Bo
    Pathology Department in School of Basic Medical Science, Peking University Health Science Center
  • LU Anhuai
    Key Laboratory of Orogenic Belts and Crustal Evolution, MOE, School of Earth and Space Sciences, Peking University

Search this article

Description

Psammoma bodies (PBs) in meningioma patients often contain mineral deposits. In this paper, the mineralogical characteristics of PBs in the mineralized focus in meningioma patients were investigated by using scanning electron microscopy (SEM), environmental scanning electron microscopy (ESEM), high-resolution transmission electron microscopy (HRTEM), energy dispersive X-ray analysis (EDAX), and electron probe microanalysis (EPMA). We found that PBs had a concentric layered structure and the size ranged from several to tens of micrometers. Although no obvious trend in the variation of Ca/P ratios was observed from the center to the outer edge of the PBs, the Ca/P ratios were much lower in the early stage of PBs formation. The concentric layered structure of the PBs might be formed by a spiral arrangement of mineralized collagen fibers. Studies on PBs mineralization may provide some supporting information in understanding the origin and development of meningiomas.

Journal

References(29)*help

See more

Keywords

Details 詳細情報について

  • CRID
    1390282681523362688
  • NII Article ID
    10029479653
  • NII Book ID
    AA11460926
  • DOI
    10.2465/jmps.110310
  • ISSN
    13493825
    13456296
  • Text Lang
    en
  • Data Source
    • JaLC
    • Crossref
    • CiNii Articles
  • Abstract License Flag
    Disallowed

Report a problem

Back to top