合成着色料の血清および肝臓コレステロール値に及ぼす影響

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書誌事項

タイトル別名
  • Influence of Artificial Food Colors on Serum and Liver Cholesterol Levels in Hypercholesterolemic Rats
  • ゴウセイ チャクショクリョウ ノ ケッセイ オヨビ カンゾウ コレステロールチ

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説明

The purpose of this study was to examine the effects of various artificial food color additives on hypercholesterolemic rats. Serum and liver cholesterol concentrations were measured in these rats fed diets containing 1% cholesterol and 0.25% bile salts.<br>As the results, the addition of 1% or 4% xanthene dyes (erythrosine, floxine, rose bengale and acid red) markedly suppresed a rise in serum and liver cholesterol levels caused by dietary cholesterol intake. In addition, the apparent accumulation ratio of the total amount of liver cholesterol to ingested cholesterol in rats received a supplement of 1% xanthene dyes decreased to about one-half of that of the cholesterol diet group. Fluorescein-Na, an analogue of these dyes, showed active hypocholesterolemic effect, whereas neither fluorescein nor fluorescein-Cl had the same effect. However, there were no cholestrol-lowering effects observed in the presence of other dyes [monoazo (amaranth and new coccine) and triphenyl methane (tartrazine, fast green FCF and sunset yellow FCF)].

収録刊行物

  • 栄養学雑誌

    栄養学雑誌 36 (5), 209-214, 1978

    特定非営利活動法人 日本栄養改善学会

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