Commentary on Japanese Pediatric Guideline for Food Allergy 2016 Chapter 11-2 Oral allergy syndrome / Chapter 11-3 Latex-fruit syndrome

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  • Nakajima Yoichi
    Department of Pediatrics, Fujita Health University
  • Ohya Yukihiro
    Division of Allergy, Department of Medical Subspecialties, National Center for Child Health and Development

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  • 第11-2章 口腔アレルギー症候群 (OAS) ／第11-3章 ラテックス–フルーツ症候群

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Abstract

<p> Oral allergy syndrome is an IgE mediated immediate food allergy of which reaction is localized to the oral mucous membrane. In this chapter, it is defined as pollen-food allergy syndrome (PFAS) which affects patients with pollen allergy. The common causative foods include fresh fruits, vegetables, and legumes and allergens include Bet v 1 homologs and profilin, which show cross-antigenicity with pollens. Thorough history taking and identifying antigen-specific IgE antibodies can help achieve a definitive diagnosis. To identify specific IgE antibodies, a prick-prick test using fresh vegetables and fruits is superior to measuring antigen-specific IgE antibodies in the blood. An elimination diet is the basis of treatment ; however, many heat-treated foods can be orally ingested.</p><p> Since 30～50% of patients with latex allergy are reported to have hypersensitive reactions to fruits and vegetables, these cases are also referred to as latex-fruit syndrome.</p>

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