Time-spatial Labeling Inversion Pulse (Time-SLIP) with Pencil Beam Pulse: A Selective Labeling Technique for Observing Cerebrospinal Fluid Flow Dynamics

  • Shibukawa Shuhei
    Department of Radiology, Tokai University Hospital Division of Health Sciences, Graduate School of Medical Science, Kanazawa University
  • Miyati Tosiaki
    Division of Health Sciences, Graduate School of Medical Science, Kanazawa University
  • Niwa Tetsu
    Department of Radiology, Tokai University School of Medicine
  • Matsumae Mitsunori
    Department of Neurosurgery, Tokai University School of Medicine
  • Ogino Tetsuo
    Philips Electronics Japan Ltd., Healthcare
  • Horie Tomohiko
    Department of Radiology, Tokai University Hospital
  • Imai Yutaka
    Department of Radiology, Tokai University School of Medicine
  • Muro Isao
    Department of Radiology, Tokai University Hospital

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<p>We assessed labeling region selectivity on time-spatial labeling inversion pulse (Time-SLIP) with pencil beam pulse (PB Time-SLIP) for the use of visualizing cerebrospinal fluid (CSF) flow dynamics. We compared the selectivity of labeling to the third and fourth ventricles between PB Time-SLIP and conventional Time-SLIP (cTime-SLIP) in eight volunteers and one patient using a 1.5T MRI. PB Time-SLIP provided more selective labeling in CSF than cTime-SLIP, particularly in complex anatomical regions.</p>

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