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- Araki Mayumi
- Keiyu Hospital Pediatrics Saitama City Hospital Pediatrics
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- Hamahata Yuko
- Saitama City Hospital Pediatrics
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- Usui Machiko
- Saitama City Hospital Pediatrics
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- Akashi Masayuki
- Saitama City Hospital Pediatrics
Bibliographic Information
- Other Title
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- 食物アレルギーによるアナフィラキシー患者におけるアドレナリン複数回投与の必要性
- ショクモツ アレルギー ニ ヨル アナフィラキシー カンジャ ニ オケル アドレナリン フクスウカイ トウヨ ノ ヒツヨウセイ
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Description
<p>Background: The aim of this study was to determine the rate, characteristics, and risk factors in patients who required multiple doses of adrenaline for treatment of anaphylaxis.</p><p>Methods: We retrospectively reviewed the positive oral food challenges (OFCs) with anaphylaxis in pediatric patients at Saitama City Hospital between January 2013 and November 2014, analyzing age, sex, comorbid allergic disease, specific IgE level, food, symptoms, and treatment.</p><p>Result: There were 42 positive challenges with anaphylaxis, and the median age of the patients was 4 years old. Eighteen patients were treated with adrenaline, 5 of whom (11.9% of anaphylaxis cases) were administered multiple doses of adrenaline. Among the 5 patients, 3 were treated with infusion. We compared patients who were not administered adrenaline or were administered a single dose of adrenaline with those who were administered multiple doses of adrenaline. No significant differences were found among the groups in relation to age, sex, comorbid allergic disease, and the aim of OFCs. The number of patients who received multiple doses of adrenaline treatment was more in the milk OFCs than the other foods OFCs. Cardiovascular and neurological symptoms were more severe in patients who received multiple doses of adrenaline.</p><p>Conclusion: Information that multiple doses of adrenaline may be required at the time of anaphylaxis should be widely disseminated.</p>
Journal
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- Japanese Journal of Allergology
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Japanese Journal of Allergology 67 (6), 751-758, 2018
Japanese Society of Allergology
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Details 詳細情報について
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- CRID
- 1390282763021628032
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- NII Article ID
- 130007405851
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- NII Book ID
- AN00012583
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- ISSN
- 13477935
- 00214884
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- NDL BIB ID
- 029150611
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- PubMed
- 30022784
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- PubMed
- CiNii Articles
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- Abstract License Flag
- Disallowed