Polycythemia Vera in A Cat Treated by Chemotherapy with Hydroxycarbamide

DOI

Bibliographic Information

Other Title
  • ヒドロキシカルバミドによる化学療法を実施した真性赤血球増加症の猫の１例

Search this article

Description

<p>A 3-year-old cat with a history of persistent erythrocytosis（PCV, 73％）was referred to our hospital. The cat did not show signs of dehydration. Secondary erythrocytosis was excluded by normal percutaneous oxygen saturation (98％) and low serum erythropoietin levels. Bone marrow examination revealed a marked increase in erythroid cells. The cat was diagnosed with polycythemia vera. X-chromosome inactivation pattern（XCIP）analysis of the androgen receptor (AR) gene in bone marrow and peripheral blood samples did not reveal clonality. The presence of JAK2 V617F mutation was not confirmed. Chemotherapy with hydroxycarbamide brought PCV under remission; the medication is still ongoing after over one year.</p>

Journal

Keywords

Details 詳細情報について

Report a problem

Back to top