A case of large central mucoepidermoid carcinoma in the mandible considered to induce attack of syncope

  • EGUCHI Takanori
    Department of Oral and Maxillofacial Surgery, Toshibarinkan Hospital
  • BASUGI Akihiko
    Department of Oral and Maxillofacial Surgery, Toshibarinkan Hospital
  • KANAI Ikuyo
    Department of Oral and Maxillofacial Surgery, Toshibarinkan Hospital
  • MIYATA Yukinaga
    Department of Oral and Maxillofacial Surgery, Toshibarinkan Hospital
  • HASEBE Mitsuhiko
    Department of Oral and Maxillofacial Surgery, School of Dental Medicine, Tsurumi University
  • HAMADA Yoshiki
    Department of Oral and Maxillofacial Surgery, School of Dental Medicine, Tsurumi University

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Other Title
  • 失神発作を惹起したと考えられた大きな下顎骨中心性粘表皮癌の1例
  • シッシン ホッサ オ ジャッキ シタ ト カンガエラレタ オオキナ カガクコツ チュウシンセイネンヒョウヒガン ノ 1レイ

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<p>Central mucoepidermoid carcinoma is an uncommon tumor, accounting for 2% to 3% of all mucoepidermoid carcinomas. Meanwhile, a head and neck tumor rarely causes an attack of syncope. We describe a case of syncope considered to be caused by a large central mucoepidermoid carcinoma in the mandible. A 66-year-old man was referred to our clinic to receive treatment for a right mandibular lesion and to determine the cause of repeated attacks of syncope. Computed tomography showed that the right side of the mandible was remarkably expanded, and the parapharyngeal space was compressed by an expanded right mandibular tumor. Tumor biopsy was performed, and a mucoepidermoid carcinoma of the mandible was definitively diagnosed. No evidence of metastasis was evident on positron emission tomography. With the patient under general anesthesia, we performed a right hemimandibulectomy, right neck dissection, and immediate reconstruction using a pectoralis major myocutaneous flap and a reconstruction plate with condyle. We found no evidence of local recurrence or regional and distant metastasis at the 4-year postoperative follow-up. In addition, no attack of syncope occurred after the operation.</p>

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