Bone regenerative therapy in the aging society

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  • Hara Tomoya
    Department of Plastic and Reconstructive Surgery, Kansai Medical University Department of Oral Implantology, Osaka Dental University
  • Kakudo Natsuko
    Department of Plastic and Reconstructive Surgery, Kansai Medical University
  • Morimoto Naoki
    Department of Plastic and Reconstructive Surgery, Kansai Medical University
  • Kusumoto Kenji
    Department of Plastic and Reconstructive Surgery, Kansai Medical University

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Other Title
  • 高齢化社会における骨再生療法
  • Bone regenerative therapy in the aging society : especially bone regeneration using bone morphogenetic proteins
  • ―骨形成タンパク質を用いた骨再生―
  • —especially bone regeneration using bone morphogenetic proteins—

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Abstract

<p>Maxillofacial bone defects can be treated with autologous bone grafting, but there are limitations such as the amount of excisable bone and larger surgical invasiveness. To overcome these limitations, various biomaterials are tested as possible substitutions of bone graft. Furthermore, to give osteoinductivities to artificial biomaterials, bone morphogenetic protein (BMP) useful as protein has been focused. With aging of the population, the application of biomaterials will have to be necessary for the elderly. Along this stream, we have performed studies on the osteogenic ability of BMP and the relationship between osteogenic ability of BMP and aging.</p>

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