Investigation of the Mechanism for Rapid Antigen-Antibody Reaction Using Electric Field Mixing (EFM)
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- NAKAMURA Ryuta
- 秋田県産業技術センター
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- KUSUMI Takayuki
- 秋田県産業技術センター
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- OKUBO Yoshinobu
- 秋田県産業技術センター
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- NANJO Hiroshi
- 秋田大学医学部附属病院
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- MINAMIYA Yoshihiro
- 秋田大学大学院医学系研究科
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- AKAGAMI Yoichi
- 秋田県産業技術センター
Bibliographic Information
- Other Title
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- 電界撹拌技術を用いた抗原抗体反応の迅速メカニズムの解明
Description
<p>By applied electric field mixing (EFM) showed antigen-antibody reaction time in an immunohistochemical staining can be shortened from 90 minutes of conventional method to 10 minutes. In this study, EFM examined the mechanism which makes antigen-antibody reaction of an immunohistochemical staining quicken. As a result, we obtained that it has the mechanism which a reaction time of an immunohistochemical staining is shorten because antigen and antibody improve to increase the frequencies of contact under EFM compared with conventional method. Further, we investigated the effect of AC electric field is applied on antibody. As a result, it found that by applied AC electric field to antibody liquid, antibody dispersed and stabilized, therefore, staining quality is improved.</p>
Journal
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- Journal of the Japan Society for Precision Engineering
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Journal of the Japan Society for Precision Engineering 85 (2), 208-212, 2019-02-05
The Japan Society for Precision Engineering
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Keywords
Details 詳細情報について
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- CRID
- 1390282763097045504
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- NII Article ID
- 130007590595
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- ISSN
- 1882675X
- 09120289
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- Text Lang
- ja
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- Data Source
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- JaLC
- Crossref
- CiNii Articles
- KAKEN
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- Abstract License Flag
- Disallowed