A Case of Multiple Gastric Cancers and Diffuse Large B Cell Lymphoma

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  • MORI Osamu
    Department of Gastroenterology and Minimally Invasive Surgery, Juntendo University School of Medicine Department of Surgery, Tokushima Red Cross Hospital
  • ISHIBASHI Yuji
    Department of Gastroenterology and Minimally Invasive Surgery, Juntendo University School of Medicine
  • KANDA Satoshi
    Department of Gastroenterology and Minimally Invasive Surgery, Juntendo University School of Medicine
  • OKA Shinichi
    Department of Gastroenterology and Minimally Invasive Surgery, Juntendo University School of Medicine
  • OKITSU Hiroshi
    Department of Surgery, Tokushima Red Cross Hospital
  • FUKUNAGA Tetsu
    Department of Gastroenterology and Minimally Invasive Surgery, Juntendo University School of Medicine
  • HIROMOTO Takafumi
    Department of Human Pathology, Juntendo University School of Medicine

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Other Title
  • 多発胃癌と胃びまん性大細胞型B細胞リンパ腫併存の1例
  • 症例 多発胃癌と胃びまん性大細胞型B細胞リンパ腫併存の1例
  • ショウレイ タハツ イガン ト イビマンセイ ダイ サイボウガタ B サイボウ リンパシュ ヘイソン ノ 1レイ

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A 75-year-old man with epigastric discomfort and weight loss was referred to our hospital and diagnosed with gastric cancer (GC) and gastric malignant lymphoma. Upper GI endoscopy showed a protruding lesion at the anterior wall of the lesser curvature near the gastric angle and an ulcerative lesion at the lesser curvature of the gastric antrum. Both lesions were diagnosed as GC. In addition, a large ulcerative lesion extending from the upper to lower gastric body near the greater curvature was diagnosed as B cell lymphoma.<BR>Cervical, thoracic, and abdominal CT showed wall thickening from the gastric body to the antrum, as well as partially indistinct margins with the transverse colon. Lymph nodes along the lesser curvature and near the right gastroepiploic artery were enlarged, and ascites was present. The diagnosis was multiple GCs and gastric malignant lymphoma, and a total gastrectomy was performed. Histopathology showed well-differentiated adenocarcinoma at two sites (pStage IA, pStage IB) and diffuse large B cell lymphoma (Lugano classification : Stage IIE, transverse colon invasion, ascites cytology positive).<BR>This very rare case of multiple GCs together with gastric malignant lymphoma is reported along with a discussion of the relevant literature.

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