Philadelphia chromosome-positive acute lymphoblastic leukemia relapsing with an anterior chamber lesion of the eye

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  • KATAYAMA Oju
    Department of Medical Oncology and Hematology, Oita University Faculty of Medicine
  • YOKOYAMA Katsuhiko
    Department of Ophthalmology, Oita University Hospital
  • SAKATA Masanori
    Department of Medical Oncology and Hematology, Oita University Faculty of Medicine
  • YANAI Yuka
    Department of Medical Oncology and Hematology, Oita University Faculty of Medicine
  • HONDA Shuhei
    Department of Medical Oncology and Hematology, Oita University Faculty of Medicine
  • YOSHIDA Natsumi
    Department of Medical Oncology and Hematology, Oita University Faculty of Medicine
  • NAGAMATSU Kentaro
    Department of Medical Oncology and Hematology, Oita University Faculty of Medicine
  • TAKANO Kuniko
    Department of Medical Oncology and Hematology, Oita University Faculty of Medicine
  • KAWANO Rie
    Department of Medical Oncology and Hematology, Oita University Faculty of Medicine
  • OGATA Masao
    Department of Hematology, Oita University Hospital
  • SHIRAO Kuniaki
    Department of Medical Oncology and Hematology, Oita University Faculty of Medicine

Bibliographic Information

Other Title
  • 前眼房病変で再発したフィラデルフィア染色体陽性急性リンパ芽球性白血病
  • ゼン ガン ボウ ビョウヘン デ サイハツ シタ フィラデルフィア センショクタイ ヨウセイ キュウセイ リンパ ガキュウセイ ハッケツビョウ

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Abstract

<p>A 48-year-old Filipino woman underwent umbilical cord blood stem cell transplantation for Philadelphia chromosome-positive acute lymphoblastic leukemia under non-remission status. Left aqueous humor puncture was performed owing to the development of left eye pain and exacerbation of anterior eye chamber inflammation 72 days after the transplantation; this revealed the relapse of leukemia in the anterior chamber. Subsequently, the patient tested positive for peripheral blood minimal residual disease. Therefore, doctors should take note that anterior chamber disease may appear as a non-typical relapse of leukemia.</p>

Journal

  • Rinsho Ketsueki

    Rinsho Ketsueki 60 (2), 134-136, 2019

    The Japanese Society of Hematology

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