- 【Updated on May 12, 2025】 Integration of CiNii Dissertations and CiNii Books into CiNii Research
- Trial version of CiNii Research Automatic Translation feature is available on CiNii Labs
- Suspension and deletion of data provided by Nikkei BP
- Regarding the recording of “Research Data” and “Evidence Data”
Reconsideration of dual allergen exposure hypothesis : Future research direction
-
- Ohshima Yusei
- Department of Pediatrics, Faculty of Medical Sciences, University of Fukui
Bibliographic Information
- Other Title
-
- 二重抗原曝露仮説を再考する : これからの研究の方向性
Search this article
Description
<p> Since dual allergen exposure hypothesis was proposed, percutaneous sensitization has attracted attention as a principal mechanism involved in the development of food allergy. Several clinical trials have been conducted to prevent food allergy by improving skin barrier function with moisturizers. However, even if suppressing the onset of atopic dermatitis, their preventive effects on the development of food allergy have not been proven. Because not all patients with food allergies have history of atopic dermatitis or impaired skin barrier function, other routes instead of skin may play a role in establishing antigen-sensitization. In pollen-food allergy syndrome, sensitization to pollen antigens, which exhibit cross reactivity with food antigens presumably occurs through respiratory tracts. Therefore, it is difficult to completely prevent the development of food allergy by intervention focusing on percutaneous sensitization. To prevent food allergies, it is necessary to clarify the factors which affect percutaneous sensitization, and the mechanism involved in oral and/or respiratory sensitization.</p>
Journal
-
- Nihon Shoni Arerugi Gakkaishi. The Japanese Journal of Pediatric Allergy and Clinical Immunology
-
Nihon Shoni Arerugi Gakkaishi. The Japanese Journal of Pediatric Allergy and Clinical Immunology 33 (1), 35-40, 2019
THE JAPANESE SOCIETY OF PEDIATRIC ALLERGY AND CLINICAL IMMUNOLOGY
- Tweet
Keywords
Details 詳細情報について
-
- CRID
- 1390282763118895360
-
- NII Article ID
- 130007628905
-
- ISSN
- 18822738
- 09142649
-
- Text Lang
- ja
-
- Article Type
- journal article
-
- Data Source
-
- JaLC
- Crossref
- CiNii Articles
- KAKEN
- OpenAIRE
-
- Abstract License Flag
- Disallowed