Sleep Disordered Breathing and Cardiovascular Diseases
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- Yoshihisa Akiomi
- Department of Cardiovascular Medicine, Fukushima Medical University Department of Advanced Cardiac Therapeutics, Fukushima Medical University
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- Takeishi Yasuchika
- Department of Cardiovascular Medicine, Fukushima Medical University
Bibliographic Information
- Other Title
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- Sleep disordered breathing cardiovascular diseases
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Description
<p>Sleep disordered breathing (SDB), which causes sleep deprivation, intermittent hypoxia, and negative intrathoracic pressure swings, can be accompanied by other harmful pathophysiologies relating to cardiovascular diseases (CVD), including sudden death, atrial fibrillation, stroke, and coronary artery disease leading to heart failure. Continuous positive airway pressure (CPAP) therapy for SDB has been reported to provide favorable effects such as lowered systemic blood pressure and improved endothelial function. However, in recent randomized controlled trials, CPAP has failed to demonstrate its beneficial prognostic impact on the primary or secondary setting of CVD. In this review article, we describe the characteristics of SDB complicated with CVD, the prognostic impacts of SDB in CVD, and the beneficial effects of CPAP on CVD.</p>
Journal
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- Journal of Atherosclerosis and Thrombosis
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Journal of Atherosclerosis and Thrombosis 26 (4), 315-327, 2019-04-01
Japan Atherosclerosis Society
