高IgG4血症及びリンパ節へのIgG4陽性形質細胞浸潤を認めた抗SS-A抗体陰性/抗SS-B抗体陽性シェーグレン症候群の1例

DOI
  • Horai Yoshiro
    Department of Rheumatology, National Hospital Organization Nagasaki Medical Center Clinical Research Center, National Hospital Organization Nagasaki Medical Center Department of Immunology and Rheumatology, Division of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences
  • Izumi Yasumori
    Department of General Internal Medicine, National Hospital Organization Nagasaki Medical Center
  • Michitsuji Tohru
    Department of General Internal Medicine, National Hospital Organization Nagasaki Medical Center Department of Rheumatology, Sasebo City General Hospital
  • Iwanaga Nozomi
    Department of Rheumatology, National Hospital Organization Nagasaki Medical Center
  • Nakashima Yoshikazu
    Department of Rheumatology, Japanese Red Cross Nagasaki Genbaku Hospital
  • Nakamura Hideki
    Department of Immunology and Rheumatology, Division of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences
  • Kawakami Atsushi
    Department of Immunology and Rheumatology, Division of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences
  • Ito Masahiro
    Department of Pathology, National Hospital Organization Nagasaki Medical Center

書誌事項

タイトル別名
  • Anti-SS-A antibody-negative/anti-SS-B antibody-positive Sjögrenʼs syndrome with increased serum concentration and lymph node infiltration of immunoglobulin G4: a case report

この論文をさがす

抄録

<p>　60歳代, 男性．当科紹介約２年前から手足しびれを自覚，また高γグロブリン血症を認めていた．血清IgG4 650mg/dLと高値，鼠経リンパ節に成熟形質細胞の増殖を認めIgG4/IgG 40-50%であった．抗SS-A抗体は陰性だったが抗SS-B抗体は陽性，口唇小唾液腺生検所見はSSに合致した．抗SS-A抗体陰性/抗SS-B抗体陽性SSにおけるIgG4の意義については更なる検討の余地があると考えられる．</p>

収録刊行物

  • 臨床リウマチ

    臨床リウマチ 30 (4), 276-283, 2018-12-30

    一般社団法人 日本臨床リウマチ学会

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ