A Case Report of Luminal A Male Inflammatory Breast Cancer that Was Difficult to Treat Because of Trousseau Syndrome

DOI IR Web Site Web Site PubMed 2 References
  • TASHIMA Yuko
    Second Department of Surgery, School of Medicine, University of Occupational and Environmental Health, Japan.
  • KUSANAGI Kasumi
    Second Department of Surgery, School of Medicine, University of Occupational and Environmental Health, Japan.
  • TAKEDA Yusuke
    Second Department of Surgery, School of Medicine, University of Occupational and Environmental Health, Japan.
  • YOSHIMATSU Katsuma
    Second Department of Surgery, School of Medicine, University of Occupational and Environmental Health, Japan.
  • ISHIDA Teruaki
    Second Department of Surgery, School of Medicine, University of Occupational and Environmental Health, Japan.
  • SHINOHARA Shinji
    Second Department of Surgery, School of Medicine, University of Occupational and Environmental Health, Japan.
  • HIRAI Ayako
    Second Department of Surgery, School of Medicine, University of Occupational and Environmental Health, Japan.
  • IMANISHI Naoko
    Second Department of Surgery, School of Medicine, University of Occupational and Environmental Health, Japan.
  • ICHIKI Yoshinobu
    Second Department of Surgery, School of Medicine, University of Occupational and Environmental Health, Japan.
  • TANAKA Fumihiro
    Second Department of Surgery, School of Medicine, University of Occupational and Environmental Health, Japan.

Bibliographic Information

Other Title
  • 炎症性乳癌とTrousseau症候群をきたし治療に難渋したLuminal A男性乳癌の1例
  • 症例報告 炎症性乳癌とTrousseau症候群をきたし治療に難渋したLuminal A男性乳癌の1例
  • ショウレイ ホウコク エンショウセイ ニュウガン ト Trousseau ショウコウグン オ キタシ チリョウ ニ ナンジュウ シタ Luminal A ダンセイ ニュウガン ノ 1レイ

Search this article

Abstract

This report describes the case of a 67-year-old male with inflammatory breast cancer. He had noticed a left breast mass about seven years previously, but he had ignored it. He then visited our hospital 4 months previously when multiple small masses occurred in the left front chest wall. The tumor was diagnosed as skin metastasis of breast cancer by skin biopsy and he was referred to our department. The tumor cells were positive for estrogen receptor and progesterone receptor, and negative for HER2/neu, and the Ki67 expression was 10-15%. The subtype of his breast cancer was luminal A type. It had secondary inflammatory breast cancer and preceded chemotherapy. Also, as the veins in the lower extremity were filled with thrombus, we gave him an anticoagulant (Edoxaban), but due to the malignant hyper coagulable state (Trousseau syndrome) a CV port could not be implanted. 3 courses of docetaxel every 3 weeks failed to control the disease. Since an obstruction of the right iliac artery was newly observed, the anticoagulant was changed to cilostazol and rivaroxaban, but left second finger and fourth finger necrosis occurred due to peripheral circulatory failure. The condition of the disease was stabilized by FEC (5-FU, epirubicin, cyclophosphamide) therapy, but it became difficult to secure the blood vessel. Without constructing a CV port because of the thrombus, chemotherapy was changed to S-1 oral administration, and strength to the chest wall Modulated radiotherapy intensity modulated radiation therapy (IMRT) was performed. Although the tumor was reduced, the condition of the whole body gradually weakened and the patient died a year and a half after the start of the treatment. This case of inflammatory luminal in male breast cancer that caused thrombus was difficult to treat. Thrombosis in advanced cancer patients is often pointed out, but since male breast cancer patients tend to take a long time to visit the hospital after becoming aware of the mass and arrive at an advanced state, it is necessary to notify the public of the existence of male breast cancer.

Journal

  • Journal of UOEH

    Journal of UOEH 41 (2), 211-216, 2019-06-01

    The University of Occupational and Environmental Health, Japan

References(2)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top