A Case of Marine-Lenhart Syndrome with Predominance of Plummer Disease

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  • MIYAZAKI Megumi
    First Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health, Japan.
  • OKADA Yosuke
    First Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health, Japan.
  • TORIMOTO Keiichi
    First Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health, Japan.
  • TANAKA Yoshiya
    First Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health, Japan.

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Other Title
  • プランマー病の病勢が優位と考えられたマリン－レンハルト症候群の1例
  • Case Report : A Case of Marine-Lenhart Syndrome with Predominance of Plummer Disease

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Description

A 74-year-old woman with a left neck mass and thyrotoxicosis was referred to our hospital, and was later diagnosed with Marine-Lenhart syndrome based on positivity for thyroid autoantibodies, ultrasonographically evident left lobe thyroid nodule with increased blood flow, and scintigraphically identified not only increased tumor-like accumulation but also diffused uptake. Disease control was difficult despite administration of antithyroid drugs, so subtotal thyroidectomy was performed. No hyperplastic changes or histopathological findings characteristic of Graves disease were evident on histopathology, so Plummer disease was considered to be dominant. In case of hot in low type which showed higher uptake in the nodule and lower uptake in the extranodular part on scintigraphy, there is a possibility of relapse in drug treatment.

Journal

  • Journal of UOEH

    Journal of UOEH 41 (2), 165-170, 2019-06-01

    University of Occupational and Environmental Health, Japan

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