A CASE OF EOSINOPHILIC ESOPHAGITIS THAT TRANSFORMED FROM THE LOCALIZED TYPE TO THE DIFFUSE TYPE

DOI
  • KOJIMA Shinichi
    Department of Gastroenterology and Hepatology, Mie University Hospital, Mie University Graduate School of Medicine.
  • KATSURAHARA Masaki
    Department of Endoscopic Medicine, Mie University Hospital, Mie University Graduate School of Medicine.
  • TAKEUCHI Toshihumi
    Department of Gastroenterology and Hepatology, Mie University Hospital, Mie University Graduate School of Medicine.
  • YAMADA Reiko
    Department of Gastroenterology and Hepatology, Mie University Hospital, Mie University Graduate School of Medicine.
  • NAKAMURA Misaki
    Department of Gastroenterology and Hepatology, Mie University Hospital, Mie University Graduate School of Medicine.
  • HAMADA Yasuhiko
    Department of Gastroenterology and Hepatology, Mie University Hospital, Mie University Graduate School of Medicine.
  • INOUE Hiroyuki
    Department of Gastroenterology and Hepatology, Mie University Hospital, Mie University Graduate School of Medicine.
  • TANAKA Kyousuke
    Department of Endoscopic Medicine, Mie University Hospital, Mie University Graduate School of Medicine.
  • HORIKI Noriyuki
    Department of Endoscopic Medicine, Mie University Hospital, Mie University Graduate School of Medicine.
  • TAKEI Yoshiyuki
    Department of Gastroenterology and Hepatology, Mie University Hospital, Mie University Graduate School of Medicine.

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Other Title
  • 下部限局型からびまん性型へ進展した好酸球性食道炎の１例

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Abstract

<p>The case was a 46-year-old female. Screening upper gastrointestinal endoscopy revealed discolored mucosa localized to the lower esophagus. An intraepithelial neoplasia was suspected, and she was referred to our hospital for close examination. Since the previous doctor detected eosinophilic infiltration by biopsy, we considered the possibility of eosinophilic esophagitis and started administration of esomeprazole. Eight weeks later, endoscopy showed that multiple discolored lesions in the mucosa and longitudinal grooves had spread over the area from the upper esophagus to the lower esophagus, resulting in the diagnosis of eosinophilic esophagitis. In recent years, the concept of localized eosinophilic esophagitis in the lower esophagus has been proposed and the possibility that eosinophilic esophagitis is an early form of esophageal eosinophilic inflammation has been pointed out. The endoscopic findings at the time of the screening endoscopic examination suggested localized lower esophageal eosinophilic inflammation. In this case, we were able to observe the natural course of diffusely spreading esophageal eosinophilic inflammation in the lower esophagus.</p>

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