Utility of the prognostic prediction model at the terminal stage of hepatocellular carcinoma

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  • 肝細胞癌終末期における予後予測モデルの有用性に関する検討
  • カン サイボウ ガン シュウマツキ ニ オケル ヨゴ ヨソク モデル ノ ユウヨウセイ ニ カンスル ケントウ

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<p>We performed a retrospective validation and accuracy study for the prognosis prediction model in 100 end-stage hepatocellular carcinoma patients who underwent palliative care at our hospital. Using the receiver operating characteristic analysis and the area under the curve (AUC), we selected the cut-off value for 3-week survival, and the predictive ability was evaluated using sensitivity, specificity, positive predictive value, negative predictive value, and accurate diagnosis rate. An examination of the various models showed that the Palliative Prognostic Index and the Biological Prognostic Score (BPS) version 3 had excellent predictive performance with AUC 0.89 and 0.82, respectively and diagnostic accuracy rate of 80 and 79, respectively. The BPS version 2 and Model for End-Stage Liver Disease score had fair predictive performance with AUC 0.72 and 0.71, respectively, and diagnostic accuracy rate of 72 and 70, respectively. The use of these models enables the stratification of prognostic prediction.</p>

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  • Kanzo

    Kanzo 60 (7), 229-236, 2019-07-01

    The Japan Society of Hepatology

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