ドパミントランスポータSPECT における各補正法が specific binding ratio およびstandardized uptake value に及ぼす影響

DOI Web Site Web Site PubMed 参考文献12件 オープンアクセス
  • 塩川 暁大
    金沢大学医薬保健学域保健学類放射線技術科学専攻(現　JA 長野厚生連佐久総合病院佐久医療センター診療放射線科)
  • 小野口 昌久
    金沢大学医薬保健研究域保健学系医療科学領域量子医療技術学講座
  • 澁谷 孝行
    金沢大学医薬保健研究域保健学系医療科学領域量子医療技術学講座
  • 前田 優汰
    金沢大学大学院医薬保健学総合研究科量子医療技術学講座(現　社会福祉法人函館厚生院函館五稜郭病院放射線科)
  • 米山 寛人
    金沢大学附属病院放射線部
  • 小西 貴広
    金沢大学附属病院放射線部
  • 若林 大志
    金沢大学附属病院核医学診療科

書誌事項

タイトル別名
  • Influence of the Each Correction Method for the Specific Binding Ratio and Standardized Uptake Value in the Dopamine Transporter SPECT
  • 臨床技術 ドパミントランスポータSPECTにおける各補正法がspecific binding ratioおよびstandardized uptake valueに及ぼす影響
  • リンショウ ギジュツ ドパミントランスポータ SPECT ニ オケル カク ホセイホウ ガ specific binding ratio オヨビ standardized uptake value ニ オヨボス エイキョウ

この論文をさがす

説明

<p>This study was to reveal the characteristics for each correction effect of specific binding ratio (SBR) and standardized uptake value (SUV) in the dopamine transporter (DAT) single photon emission computed tomography (SPECT). We created the 123I solution of five radioactive concentrations, which was filled with two types of striatum phantom such as separated or integrated caudate and putamen. We created 10 striatum accumulation models by combining the 123I solution. Images were reconstructed using ordered subset expectation maximization (OSEM) incorporating attenuation correction (AC), scatter correction (SC) or resolution recovery (RR) for the collected data of 10 striatum accumulation models and 66 patients. Correction combinations were AC, ACSC, ACRR and ACSCRR. The SBR, SUVmean and SUVmax were evaluated correlation and relative error between SBR, SUVmean and SUVmax by each correction method. The SBR and SUV had a significant positive correlation with all correction methods. The minimum values of relative error for SBR, SUVmean and SUVmax were 39.7% with ACSCRR, 18.4% with AC and 16.5% with ACSC, respectively. In addition, the ACSC of SBR and SUVmean was almost same value. The SBR showed significantly higher values by incorporating SC, while the SUV was significantly higher values by incorporating RR. It was suggested that SUV could be used for the quantitative index of DAT SPECT. Furthermore, we demonstrated the characteristic among each correction for SBR and SUV.</p>

収録刊行物

参考文献 (12)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ