Reduction of Fluctuation of the Binding Activity of SGP to Influenza Viruses

DOI Web Site Web Site 19 References Open Access
  • KAWAHARA Toshio
    College of Life and Health Sciences, Chubu University Graduate School of Engineering, Chubu University
  • HIRAMATSU Hiroaki
    College of Life and Health Sciences, Chubu University
  • OHMI Yuhsuke
    College of Life and Health Sciences, Chubu University
  • SUZUKI Yasuo
    College of Life and Health Sciences, Chubu University
  • HAYASHI Kyoko
    Graduate School of Engineering, Chubu University
  • NAKAKITA Shin-ichi
    Life Science Research Center, Kagawa University
  • WATANABE Yohei
    Graduate School of Medical Sciences, Kyoto Prefectural University of Medicine
  • OHNO Yasuhide
    Graduate School of Science and Technology, Tokushima University
  • MAEHASHI Kenzo
    Institute of Engineering, Tokyo University of Agriculture and Technology
  • ONO Takao
    The Institute of Scientific and Industrial Research, Osaka University
  • KANAI Yasushi
    The Institute of Scientific and Industrial Research, Osaka University
  • MATSUMOTO Kazuhiko
    The Institute of Scientific and Industrial Research, Osaka University

Bibliographic Information

Other Title
  • インフルエンザウイルスセンサのためのsialylglycopeptideのbovine serum albumin固定化によるゆらぎの低減
  • インフルエンザウイルスセンサ ノ タメ ノ sialylglycopeptide ノ bovine serum albumin コテイカ ニ ヨル ユラギ ノ テイゲン

Search this article

Description

<p>For biosensors with host specificity for influenza viruses, we used sugar chains with different coordinations of terminal sialic acid and penultimate galactose. Sialylglycopeptide (SGP) is one of the candidates for detecting molecules in the biosensors for influenza viruses, and we have investigated the host specificity of the viruses using an enzyme-linked immunosorbent assay (ELISA). Using the bovine serum albumin (BSA) localization, we have obtained the stable distribution. The clustering of sugar chains could also enhance and stabilize the binding activity. Comparing with single sugar chains of SGP, clusterized molecules of SGP-BSA showed the reduction of relative errors in the fluctuation in binding activity.</p>

Journal

  • Vacuum and Surface Science

    Vacuum and Surface Science 62 (8), 470-475, 2019-08-10

    The Japan Society of Vacuum and Surface Science

References(19)*help

See more

Related Projects

See more

Keywords

Details 詳細情報について

Report a problem

Back to top