Workersʼ Lifestyles and Urinary 8-hydroxydeoxyguanosine as an Oxidative Stress Marker

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  • WATANABE Sintaroo
    Department of Environmental Oncology Institute of Industrial Ecological Sciences, University of Occupational and Environmental Health, Japan Japan Marine United Corporation Kure Shipyard
  • LI Yun-Shan
    Department of Environmental Oncology Institute of Industrial Ecological Sciences, University of Occupational and Environmental Health, Japan
  • KAWASAKI Yuya
    Department of Environmental Oncology Institute of Industrial Ecological Sciences, University of Occupational and Environmental Health, Japan
  • KAWAI Kazuaki
    Department of Environmental Oncology Institute of Industrial Ecological Sciences, University of Occupational and Environmental Health, Japan

Bibliographic Information

Other Title
  • 労働者の生活習慣が生体内酸化ストレスに及ぼす影響
  • ロウドウシャ ノ セイカツ シュウカン ガ セイタイナイ サンカ ストレス ニ オヨボス エイキョウ
  • Workers’ Lifestyles and Urinary 8-hydroxydeoxyguanosine as an Oxidative Stress Marker

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Description

Oxidative stress in biological components has become recognized as one of the causative factors of various diseases. In this study, we investigated the effects of worker lifestyle and fatigue on the levels of urinary 8-hydroxydeoxyguanosine (8-OHdG), a marker of oxidative stress. Our results revealed that urinary 8-OHdG level was increased by alcohol intake and decreased by snack intake and adequate sleep time on the day before the survey. A decrease in urinary 8-OHdG level was also observed in parallel with a decrease in workload. Urinary 8-OHdG monitoring is expected to be useful for disease prevention in the future.

Journal

  • Journal of UOEH

    Journal of UOEH 41 (4), 431-436, 2019-12-01

    University of Occupational and Environmental Health, Japan

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