Diffusion in Cells or Biomembranes―Diffusion Enhancement and Drift Induced by Hydrodynamical Collective Effect

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  • 生体内の拡散ダイナミクス―協同的流体力学効果がもたらす拡散促進・凝集
  • セイタイナイ ノ カクサン ダイナミクス : キョウドウテキ リュウタイ リキガク コウカ ガ モタラス カクサン ソクシン ・ ギョウシュウ

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Abstract

<p>Recently, the diffusion processes in a cell were observed by direct tracking of particles inside a cell. The experimental results imply that the diffusion inside a cell is enhanced by activity of proteins. Mikhailov and Kapral proposed a model which suggests the possible mechanism for such diffusion enhancement. In the model, the conformational change of proteins is considered to induce fluctuating flow, that enhances diffusion. Moreover, when proteins are distributed non-uniformly, they induce not only diffusion enhancement but also the drift velocity of tracer particles. When there is a cluster of proteins with conformational change, the tracer particles tend to be accumulated into the cluster.</p>

Journal

  • Butsuri

    Butsuri 74 (9), 627-632, 2019-09-05

    The Physical Society of Japan

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