THE EFFECTIVENESS OF ACUTE NORMOVOLEMIC HEMODILUTION (ANH) FOR AORTIC VALVE STENOSIS SURGERY

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  • Iwasa Shizuko
    Department of Cardiovascular Surgery, Hokkaido Cardiovascular Hospital
  • Sato Junichi
    Department of Anesthesiology, Hokkaido Cardiovascular Hospital
  • Yamazaki Kenji
    Department of Cardiovascular Surgery, Hokkaido Cardiovascular Hospital
  • Nojima Masahiro
    Center for Translational Research/Division of Advanced Medicine Promotion, Institute of Medical Science, University of Tokyo

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  • 大動脈弁狭窄症に対する大動脈弁置換術における希釈式自己血輸血の有用性

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<p>Objective: We retrospectively assessed the efficacy of acute normovolemic hemodilution (ANH) for aortic valve stenosis surgery from the medical perspective.</p><p>Methods: In this study, we analyzed 42 patients who required aortic valve replacements for aortic valve stenosis between April 2016 and February 2019. We performed ANH in February 2018. Patients were divided into 2 groups as follows: group A patients on whom ANH was performed (n=18) and group C patients on whom ANH was not performed before February 2018 (n=24).</p><p>Results: There was no significant difference in the pre-operative patient background information between the 2 groups. The amount of post-operative bleeding and volume of post-operative blood transfused were significantly higher in group C patients than those in group A patients. The duration of inotropic agent infusion was not significantly different between the 2 groups.</p><p>Discussion: ANH for aortic stenosis might pose a risk of hemodynamic instability to the patient as he might have anemia. Our study was unable to show elongation of inotropic agent infusion or hemodynamic instability in these patients.</p><p>Conclusion: ANH might be performed for aortic valve stenosis if it is safe for the patient and contributes to reduction in the use of allogeneic blood products. It might also be beneficial for post-operative recovery.</p>

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