A trial of oral food challenge tests safely performed for non-allergy specialists

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  • アレルギー非専門医が安全に行える食物経口負荷試験の試み

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Abstract

<p>Oral food challenge tests (OFC) are essential for the management of food allergic patients. However, there are not so enough allergy specialists that we have made OFC manuals safely operated for non-allergy specialists in the Committee of Maternal and Child Health Care in Fukuoka City Medical Association. In this manual, allergens are limited in egg, milk and wheat. And, subjects are limited in patients of complete avoidance whose specific IgE antibody (sIgE) levels are as follows: in case of egg allergy class of egg-white sIgE≤2 and ovamucoid≤2; in case of milk allergy sIgE class of milk≤2; and in case of wheat allergy sIgE class of wheat≤3 and ω5-gliadin≤1. In the case of patients who have already taken some allergens, it is designed to start OFC with half quantities of already taken foods.</p><p>Under these conditions, OFC were performed for 42 patients in our clinic. In the patients of complete avoidance, 8 cases of egg allergy, 6 cases of milk allergy, and 6 cases of wheat allergy did not show any reactions. Only one case of wheat allergy showed slight urticaria. In 22 cases of patients who have already taken some allergens, only 1 case of egg allergy showed systemic urticaria.</p><p>These results indicate that OFC with these conditions can be performed safely by non-allergy specialists.</p>

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