IgA Vasculitis Triggered by Infective Endocarditis of Pulmonary Artery with Congenitally Corrected Transposition of the Great Arteries
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- Akagi Midori
- Department of General Internal Medicine, National Hospital Organization Nagasaki Medical Center Department of Rheumatology, JCHO Isahaya General Hospital
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- Iwanaga Nozomi
- Department of Rheumatology, National Hospital Organization Nagasaki Medical Center
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- Torisu Yuichi
- Department of General Internal Medicine, National Hospital Organization Nagasaki Medical Center
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- Fujita Hisayuki
- Physiological Laboratory, National Hospital Organization Nagasaki Medical Center
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- Kawahara Chieko
- Department of General Internal Medicine, National Hospital Organization Nagasaki Medical Center
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- Horai Yoshiro
- Department of Rheumatology, National Hospital Organization Nagasaki Medical Center Clinical Research Center, National Hospital Organization Nagasaki Medical Center
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- Izumi Yasumori
- Department of General Internal Medicine, National Hospital Organization Nagasaki Medical Center
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- Kawakami Atsushi
- Department of Immunology and Rheumatology, Division of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences
書誌事項
- タイトル別名
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- A Case Report and Literature Review
説明
<p>A man in his 40s with a history of congenitally corrected transposition of the great arteries (CCTGA) and closure of ventricular septal defect was referred to our hospital with purpura and hematuria. Presence of purpura, renal damage, and pathological findings on skin biopsy led to the diagnosis of IgA vasculitis (IgAV). Oral prednisolone (PSL) was initiated. However, Streptococcus pseudoporcinus was isolated from blood cultures, and transthoracic echocardiogram revealed vegetation on the pulmonary valve. From these findings, the diagnosis of infective endocarditis (IE) was made. Although the patient's condition improved after PSL interruption and antibiotic administration, his purpura relapsed. PSL readministration improved symptoms, with no further relapse even after gradual PSL dose reduction. The present case raises awareness of the importance of recognizing the occurrence of IE in IgAV patients, especially in those with congenital heart disease. CCTGA should be acknowledged as a risk factor for IE in the right-sided heart.</p>
収録刊行物
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- International Heart Journal
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International Heart Journal 61 (2), 404-408, 2020-03-28
一般社団法人 インターナショナル・ハート・ジャーナル刊行会
