Effects of Polymer Entanglement in Sodium Hyaluronate Solution on Elastic Instability in Abrupt Contraction-Expansion Micro Channels

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  • ヒアルロン酸ナトリウムの水溶液中の絡み合いがマイクロ急縮小急拡大流路内の弾性不安定に与える影響
  • ヒアルロンサン ナトリウム ノ スイヨウエキ チュウ ノ カラミアイ ガ マイクロ キュウシュクショウ キュウカクダイ リュウロ ナイ ノ ダンセイ フアンテイ ニ アタエル エイキョウ

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Abstract

<p>In this study, the effects of polymer flexibility and entanglement on elastic instability were investigated by observing sodium hyaluronate (Hyaluronic Acid Sodium salt, Na-HA) solution in planar abrupt contraction-expansion microchannels. The rigidity of Na-HA in a solution is affected by ion concentration in the solution. Therefore, we prepared Na-HA water solution and Na-HA PBS solution with concentrations from 0.15 wt% to 0.45 wt%. The rheological properties were measured and analyzed to detect the Na-HA overlap and entanglement concentrations. The flow regimes of the Na-HA solutions in several planar abrupt contraction-expansion channels were characterized in terms of rheological properties, polymer flexibility and polymer entanglement.</p>

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