Redox State Control of Human Cytoglobin by Direct Electrochemical Method to Investigate Its Function in Molecular Basis
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- Mie Yasuhiro
- Bioproduction Research Institute, National Institute of Advanced Industrial Science and Technology (AIST)
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- Takahashi Kyoka
- Bioproduction Research Institute, National Institute of Advanced Industrial Science and Technology (AIST)
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- Torii Ryo
- Graduate School of Pharmaceutical Sciences, Osaka University
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- Jingkai Shen
- Graduate School of Pharmaceutical Sciences, Osaka University
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- Tanaka Takumi
- Graduate School of Pharmaceutical Sciences, Osaka University
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- Sueyoshi Kenta
- Graduate School of Pharmaceutical Sciences, Osaka University
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- Tsujino Hirofumi
- Graduate School of Pharmaceutical Sciences, Osaka University
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- Yamashita Taku
- School of Pharmacy and Pharmaceutical Sciences, Mukogawa Women’s University
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<p>The direct electron transfer between human cytoglobin (Cygb) and the electrode surface, which would allow manipulating the oxidation states of the heme iron in Cygb, was first observed by immobilizing Cygb on a nanoporous gold (NPG) electrode via a carboxy-terminated alkanethiol. The voltammetric performances of the wild type and mutated Cygb-immobilized NPG electrodes were evaluated in the absence or presence of potential substrates. The obtained results demonstrated that the usefulness of the proposed method in understanding the function of Cygb in molecular basis.</p>
収録刊行物
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- CHEMICAL & PHARMACEUTICAL BULLETIN
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CHEMICAL & PHARMACEUTICAL BULLETIN 68 (8), 806-809, 2020-08-01
公益社団法人 日本薬学会
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詳細情報 詳細情報について
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- CRID
- 1390285300179929600
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- NII論文ID
- 130007883281
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- NII書誌ID
- AA00602100
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- ISSN
- 13475223
- 00092363
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- NDL書誌ID
- 030547777
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- PubMed
- 32461519
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
- KAKEN
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- 抄録ライセンスフラグ
- 使用不可