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- SUZUKI Nobuaki
- Department of Transfusion Medicine, Nagoya University Hospital
Bibliographic Information
- Other Title
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- 出血性後天性凝固異常症
- シュッケツセイ コウテンセイ ギョウコ イジョウショウ
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Abstract
<p>Acquired coagulation inhibitors have become a popular area of research because they cause severe bleeding tendency in many patients. The use of acquired coagulation inhibitors requires rapid and precise diagnosis. Some acquired coagulation inhibitors show prolongation in the activated partial thromboplastin time (APTT) and/or prothrombin time (PT). To diagnose these disorders, mixing test is very useful. However, lupus anticoagulant related disorders, such as lupus anticoagulant hypoprothrombinemia syndrome (LAHPS), are difficult to diagnose because they are sometimes associated with a reduction in factor VIII and are thus difficult to distinguish from acquired hemophilia. Acquired factor XIII deficiency and acquired von Willebrand syndrome (AvWS) are easily overlooked because they show normal value in several patients with APTT and PT. Here I describe the diagnostic method for these disorders. In particular, five acquired coagulation inhibitors that appear to be clinically significant are studied.</p>
Journal
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- Rinsho Ketsueki
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Rinsho Ketsueki 61 (7), 779-784, 2020
The Japanese Society of Hematology
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Keywords
Details 詳細情報について
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- CRID
- 1390285300180790528
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- NII Article ID
- 130007884761
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- NII Book ID
- AN00252940
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- ISSN
- 18820824
- 04851439
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- NDL BIB ID
- 030593962
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- PubMed
- 32759565
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- PubMed
- CiNii Articles
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- Abstract License Flag
- Disallowed