Biological and Medical Application of Intense Electromagnetic Radiation

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  • 高強度電磁エネルギーの生体・医療応用
  • コウキョウド デンジ エネルギー ノ セイタイ ・ イリョウ オウヨウ

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This paper describes the biological effect of an intense pulsed electric fi eld and electromagnetic radiation that varies by frequency band. A fi eld with less frequency than 1 MHz provides an electrical stress to the plasma membrane, but that with higher frequency is likely to affect the intracellular components. A laser plasma soft x-ray microscope, which is a combination of highly intense laser plasma soft x-ray sources and a contact type soft x-ray microscope, has been developed. The laser plasma soft x-ray microscope captures an x-ray image of live hydrated biological cells with 80-nm spatial resolution in a 600-ps time duration. Cellular organelles such as chromatin, mitochondria and actin fi laments have been observed with the laser plasma soft x-ray microscope in combination with a fl uorescence microscope to identify cellular organelles. We also observed such life phenomenon as an apoptotic process and detailed structural deformation.

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