Challenges and perspectives in clinical assessment of systemic autoimmune rheumatic diseases

DOI
  • Ueno Yasuhiro
    Faculty of Medicine, Toho University
  • Kameda Hideto
    Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Toho University

Bibliographic Information

Other Title
  • 膠原病の臨床評価における課題と展望

Abstract

<p>Systemic autoimmune rheumatic diseases including systemic lupus erythematous（SLE）are diseases of unknown cause, in which a diverse population is formed without a gold standard for each disease. Therefore, only classification criteria（for a patient group）have been created and revised, and international diagnostic criteria（for individual patient）cannot be proposed. The treatment strategy is not directly determined by the disease diagnosis, but by the severity of the disease. Severity, in turn, is determined by the prediction of poor prognosis in a relatively short term, namely the current degree of organ damage, the current activity of organ damage, the contribution of the affected organ to life and vital function, and the treatment responsiveness. It is easy to understand if activity is defined as the progression speed（time differential value）of organ damage. Although clinical evaluations currently in widespread use meet certain criteria, it is expected that they will be complemented and improved by the use of new imaging tests, biomarkers, and artificial intelligence in the future.</p>

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Keywords

Details 詳細情報について

  • CRID
    1390286426513466624
  • NII Article ID
    130007931463
  • DOI
    10.14961/cra.32.181
  • ISSN
    21890595
    09148760
  • Text Lang
    ja
  • Data Source
    • JaLC
    • CiNii Articles
  • Abstract License Flag
    Disallowed

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