重症急性咽頭・扁桃炎におけるレボフロキサシン（500 mg） 1日 1 回投与の有用性

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  • 高原 幹
    旭川医科大学耳鼻咽喉科・頭頸部外科
  • 國部 勇
    旭川医科大学耳鼻咽喉科・頭頸部外科
  • 林 達哉
    旭川医科大学耳鼻咽喉科・頭頸部外科
  • 原渕 保明
    旭川医科大学耳鼻咽喉科・頭頸部外科

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タイトル別名
  • Effectiveness of Once-daily Oral Administration of 500 mg Levofloxacin for Treatment of Adult Patients with Severe Acute Pharyngotonsillitis
  • ジュウショウ キュウセイ イントウ ・ ヘントウエン ニ オケル レボフロキサシン(500mg)1ニチ 1カイ トウヨ ノ ユウヨウセイ

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説明

<p>The efficacy of once-daily oral administration of 500 mg Levofloxacin for treatment of adult patients with severe acute pharyngotonsillitis was investigated. Thirty patients diagnosed with severe pharyngotonsillitis by a pharyngotonsillitis scoring system were enrolled in this study. Twenty-three and 7 patients were treated with internal Levofloxacin and Amoxicillin, respectively. The effectiveness of each antibacterial agent was evaluated by comparing the score before and after treatment. The score significantly decreased after treatment with each antibacterial agent. Score 0, which represents disappearance of the symptoms and no abnormal local findings, was seen in 18 (78%) patients treated with Levofloxacin; however, score 0 was seen in only one (14%) patient treated with Amoxicillin. According to these results, we concluded that once-daily oral administration of 500 mg Levofloxacin was very effective for the treatment of severe acute pharyngotonsillitis.</p>

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