Spindle Cell Carcinoma of the Breast with Early Local Recurrence after Surgery

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  • 術後早期に局所再発を認め急速な転帰をたどった乳腺紡錘細胞癌の1例
  • 症例 術後早期に局所再発を認め急速な転帰をたどった乳腺紡錘細胞癌の1例
  • ショウレイ ジュツゴ ソウキ ニ キョクショ サイハツ オ ミトメ キュウソク ナ テンキ オ タドッタ ニュウセン ボウスイ サイボウガン ノ 1レイ

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Abstract

<p>We encountered a case of spindle cell carcinoma of the breast a rare type of breast cancer with early local recurrence after surgery and rapid outcomes. A 55-year-old woman presented to our hospital with a lump in her left breast ; pathological examination indicated a spindle cell carcinoma of the breast. Preoperative imaging revealed a 24-mm tumor in the left mammary gland and no axillary lymph node or distant metastasis. The patient underwent breast-conserving surgery and sentinel lymph node biopsy for the spindle cell carcinoma of the breast (cT2N0M0 cStage IIA). During postoperative adjuvant chemotherapy, we observed an increase in the size of the lumps in the left axilla as well as skin thickening of the entire left mammary gland. The patient was diagnosed with pathological recurrence on core needle biopsy. On the 64th postoperative day, left mastectomy with partial resection of the pectoralis muscle and axillary lymph node dissection were performed because the tumor showed chemotherapy resistance and no distant metastases were observed. Postoperative pathological examination revealed that the recurrent tumor had coalesced and reached a diameter of 85 mm. Two weeks after the reoperation, skin metastasis and lymph node metastasis were found. Subsequently, radiotherapy and some chemotherapy regimens were ineffective. Eventually, the patient died 6 months after the first operation.</p>

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