聴覚性P300の刺激別発達変化；言語音と非言語音の相違

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  • Hatori Takayuki
    国立精神・神経センター精神保健研究所　知的障害部 日本医科大学　小児科
  • Inagaki Masumi
    国立精神・神経センター精神保健研究所　知的障害部
  • Shirane Seiko
    国立精神・神経センター精神保健研究所　知的障害部
  • Kaga Makiko
    国立精神・神経センター精神保健研究所　知的障害部

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タイトル別名
  • Developmental Changes of Auditory P300; Difference Between Two Stimuli Conditions, Non-verbal Sound and Verbal Sound

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説明

Developmental changes of P300 event related potential were evaluated in healthy 13 children and 19 adults aged from 7 to 29 years old, using 2 pairs of oddball stimuli; non verbal sound (tone burst: TB) pair and verbal sound (VS) pair. In both age groups, P300 was definitely present to the target stimuli and dominant at Pz for both conditions. Peak latency of P300 was significantly longer for VS than TB in both groups. P300 amplitude of child group was higher than that of the adult group. However, there was no difference of P300 amplitude between stimuli conditions. Developmental changes of P300 from each stimulus condition were simulated by a quadratic equation. The age showing the shortest P300 peak latency was younger for TB (20.3 years) than VS (23.6 years). Reduction rate of the peak latency of P300 around 10 years old was more rapid for VS than TB. In conclusion, there was no significant difference of the dominancy of P300 between the two kinds of stimulus condition. We considered that the developmental change of P300 was regulated by the several components of the sound stimuli such as frequency or familiarity.

収録刊行物

  • 精神保健研究

    精神保健研究 (16(通巻49)), 159-167, 2003-03-31

    国立研究開発法人国立精神・神経医療研究センター

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