Non-functioning pancreatic neuroendocrine tumor with stenosis of the main pancreatic duct

  • OGAWA Tomoya
    Department of gastroenterology, Saitama Medical University International Medical Center
  • RYOZAWA Shomei
    Department of gastroenterology, Saitama Medical University International Medical Center
  • MIZUIDE Masafumi
    Department of gastroenterology, Saitama Medical University International Medical Center
  • TANISAKA Yuki
    Department of gastroenterology, Saitama Medical University International Medical Center
  • FUJITA Akashi
    Department of gastroenterology, Saitama Medical University International Medical Center
  • SUZUKI Masahiro
    Department of gastroenterology, Saitama Medical University International Medical Center
  • NOGUCHI Tatsuya
    Department of gastroenterology, Saitama Medical University International Medical Center
  • KATSUDA Hiromune
    Department of gastroenterology, Saitama Medical University International Medical Center
  • NAGATA Koji
    Department of pathology, Saitama Medical University International Medical Center
  • KAWASAKI Tomonori
    Department of pathology, Saitama Medical University International Medical Center
  • AIKAWA Masayasu
    Department of gastrointestinal surgery, Saitama Medical University International Medical Center
  • OKAMOTO Kojun
    Department of gastrointestinal surgery, Saitama Medical University International Medical Center

Bibliographic Information

Other Title
  • 主膵管の狭窄を伴った膵神経内分泌腫瘍の1例

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Description

<p>A-65-year-old man with a mass in the body of the pancreas seen on ultrasonography was referred for further evaluation. Abdominal contrast-enhanced computed tomography scan revealed a 10mm enhancing lesion in the body of the pancreas along with stenosis of the main pancreatic duct stenosis near the lesion and caudal dilation. Although a pancreatic neuroendocrine tumor was suspected, we performed endoscopic ultrasonography-guided fine-needle aspiration because pancreatic ductal carcinoma could not be ruled out. Histopathological analysis revealed a PNET G1. Distal pancreatectomy was performed, and immunostaining was positive for chromogranin A, synaptophysin and serotonin. Fibrosis caused by serotonin was thought to be involved in the pathogenesis of the main pancreatic duct stenosis in this patient.</p>

Journal

  • Suizo

    Suizo 36 (2), 169-176, 2021-04-30

    Japan Pancreas Society

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