Clinical characteristics of hyponatremia in patients receiving nutrition support : A cross-sectional study evaluated by bioelectrical impedance analysis

  • Yano Mayumi
    Department of Therapeutic Nutrition, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan
  • Inoue Arisa
    Department of Therapeutic Nutrition, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan
  • Toda Akiyo
    Department of Clinical Nutrition and Dietetics, Konan Women’s University, Kobe, Japan
  • Takahashi Michiko
    Department of Nutrition, Division of Diabetes and Endocrinology Department of Internal Medicine, Kobe University Hospital, Kobe, Japan
  • Usami Makoto
    Department of Clinical Nutrition and Dietetics, Konan Women’s University, Kobe, Japan
  • Hamada Yasuhiro
    Department of Therapeutic Nutrition, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan

書誌事項

公開日
2021
資源種別
journal article
DOI
  • 10.2152/jmi.68.112
公開者
国立大学法人 徳島大学医学部

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説明

<p>Background & aims : We investigated the contributing factors of hyponatremia in patients on nutrition support using bioelectrical impedance analysis (BIA). Methods : Thirty patients administered enteral or parenteral nutrition support for at least 72 hours were studied. We collected nutritional and electrolyte intake, serum biochemical parameters, and body composition measured by BIA. Patients were classified into two groups according to their serum sodium levels : (1) Normanatremia group, 135–145 mEq / L (n = 18) and (2) Hyponatremia group, less than 135 mEq / L (n = 12), and their characteristics were analyzed. Results : There were no significant differences between the Normonatremia and Hyponatremia groups in terms of energy, protein, and sodium intake. Serum biochemical parameters other than serum sodium and chloride levels were comparable between the two groups. On the other hand, the ratio of extracellular water to total body water (ECW / TBW) obtained by BIA was significantly higher in the Hyponatremia group than in the Normonatremia group. Further, an elevated ECW / TBW significantly and negatively correlated with serum albumin level. Conclusions : Regardless of sodium intake, higher ECW / TBW was associated with hyponatremia in patients on nutrition support. ECW / TBW may be an important clinical parameter relevant to the nutritional care of hyponatremia. J. Med. Invest. 68 : 112-118, February, 2021</p>

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