Effect of Sex on Mortality and Left Ventricular Remodeling After Transcatheter Aortic Valve Implantation
-
- Shishido Koki
- Department of Cardiology, Shonan Kamakura General Hospital
-
- Yamanaka Futoshi
- Department of Cardiology, Shonan Kamakura General Hospital
-
- Ochiai Tomoki
- Department of Cardiology, Shonan Kamakura General Hospital
-
- Moriyama Noriaki
- Department of Cardiology, Shonan Kamakura General Hospital
-
- Yokoyama Hiroaki
- Department of Cardiology, Shonan Kamakura General Hospital
-
- Yokota Shohei
- Department of Cardiology, Shonan Kamakura General Hospital
-
- Noguchi Kenichiro
- Department of Cardiovascular Surgery, Shonan Kamakura General Hospital
-
- Yashima Fumiaki
- Department of Cardiology, Saiseikai Utsunomiya Hospital
-
- Tada Norio
- Department of Cardiology, Sendai Kousei Hospital
-
- Naganuma Toru
- Department of Cardiology, New Tokyo Hospital
-
- Araki Motoharu
- Department of Cardiology, Saiseikai Yokohama City Eastern Hospital
-
- Shirai Shinichi
- Department of Cardiology, Kokura Memorial Hospital
-
- Ueno Hiroshi
- Department of Cardiovascular Medicine, Toyama University School of Medicine
-
- Mizutani Kazuki
- Department of Cardiovascular Medicine, Osaka City University School of Medicine
-
- Tabata Minoru
- Department of Cardiology, Tokyo Bay Urayasu Ichikawa Medical Center
-
- Takagi Kensuke
- Department of Cardiology, Ogaki Municipal Hospital
-
- Watanabe Yusuke
- Department of Cardiology, Teikyo University School of Medicine
-
- Yamamoto Masanori
- Department of Cardiology, Toyohashi Heart Canter Department of Cardiology, Nagoya Heart Canter
-
- Saito Shigeru
- Department of Cardiology, Shonan Kamakura General Hospital
-
- Hayashida Kentaro
- Department of Cardiology, Keio University School of Medicine
この論文をさがす
説明
<p>Background:The effect of sex on mortality is controversial; furthermore, sex differences in left ventricular (LV) remodeling after transcatheter aortic valve implantation (TAVI) remain unknown.</p><p>Methods and Results:This study included 2,588 patients (1,793 [69.3%] female) enrolled in the Optimized CathEter vAlvular iNtervention (OCEAN)-TAVI Japanese multicenter registry between October 2013 and May 2017. We retrospectively analyzed the effect of sex on mortality, and evaluated changes in the LV mass index (LVMI) after TAVI. Female sex was significantly associated with lower all-cause and cardiovascular mortality (log-rank P<0.001 for both). Multivariate analysis showed that female sex was independently associated with lower cumulative long-term mortality (hazard ratio 0.615; 95% confidence interval 0.512–0.738; P<0.001). Regression in the LVMI was observed in both sexes, and there was no significant difference in the percentage LVMI regression from baseline to 1 year after TAVI between women and men. Women had a survival advantage compared with men among patients with LVMI regression at 1 year, but not among patients with no LVMI regression.</p><p>Conclusions:We found that female sex is associated with better survival outcomes after TAVI in a large Japanese registry. Although LVMI regression was observed in women and men after TAVI, post-procedural LV mass regression may be related to the sex differences in mortality.</p>
収録刊行物
-
- Circulation Journal
-
Circulation Journal 85 (7), 979-988, 2021-06-25
一般社団法人 日本循環器学会
- Tweet
キーワード
詳細情報 詳細情報について
-
- CRID
- 1390288480071203456
-
- NII論文ID
- 130008056900
-
- NII書誌ID
- AA11591968
-
- ISSN
- 13474820
- 13469843
-
- NDL書誌ID
- 031532173
-
- PubMed
- 33907051
-
- 本文言語コード
- en
-
- データソース種別
-
- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
-
- 抄録ライセンスフラグ
- 使用不可