超音波力学療法のための酸化チタンナノ粒子内包高分子ミセル

  • 原田 敦史
    大阪府立大学大学院工学研究科応用化学分野

書誌事項

タイトル別名
  • Titanium Dioxide Nanoparticles-Entrapped Polymeric Micelles for Sonodynamic Therapy
  • チョウオンパ リキガク リョウホウ ノ タメ ノ サンカ チタンナノ リュウシ ナイホウ コウブンシ ミセル

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説明

<p>In an aging society, there is an increasing need for minimally invasive treatment, which is a treatment method that minimizes the degree of physical burden. Here, we focused on the properties of titanium dioxide nanoparticles (TiO2 NPs) as a sonosensitizer and outlined polymer micelles that are effective in sonodynamic therapy by combining with synthetic polymer materials. TiO2 NPs-entrapped micelles not only exhibits a cell-killing effect through the generation of reactive oxygen species by sonication after cellular uptake but can also function as a carrier for multivalent anions or hydrophobic compounds. It is expected that such micelles have potential utilities in minimally invasive therapy.</p>

収録刊行物

  • 粉体工学会誌

    粉体工学会誌 58 (7), 384-388, 2021-07-10

    一般社団法人 粉体工学会

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