Time-Course evaluation of hepatomegaly in mice using micro-CT and the aspect interfering toxicological interpretation

DOI

Bibliographic Information

Other Title
  • micro-CTを用いたマウスにおける肝肥大の経時変化の評価ならびに撮影影響の検討

Description

<p>Micro-computed tomography (micro-CT) is an imaging modality that enable us to non-invasively obtain 3D images of organs in laboratory animals. By using micro-CT, internal organs can be monitored repeatedly, which leads to more precise evaluation and reduction in the number of animals used. In this study, we evaluated time-course of chemically-induced hepatomegaly in mice using micro-CT.</p><p>The liver volume calculated from CT images was highly correlated to the liver weight. Therefore, it was considered that CT imaging can be a useful tool for evaluating the time-course of hepatomegaly.</p>

Journal

Details 詳細情報について

  • CRID
    1390289011246197504
  • NII Article ID
    130008073846
  • DOI
    10.14869/toxpt.48.1.0_p-42
  • Text Lang
    ja
  • Data Source
    • JaLC
    • CiNii Articles
  • Abstract License Flag
    Disallowed

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