A case of malignant catatonia successfully diagnosed and treated with intravenous lorazepam

DOI Web Site 8 References Open Access
  • Nakashima Kosuke
    Emergency and Critical Care Center, Kyushu University Hospital Department of Anesthesiology and Critical Care Medicine, Kyushu University Hospital
  • Maki Jun
    Department of Critical Care Medicine, Kyushu University Hospital
  • Takahashi Keita
    Emergency and Critical Care Center, Kyushu University Hospital Department of Anesthesiology and Critical Care Medicine, Kyushu University Hospital
  • Shirozu Kazuhiro
    Department of Anesthesiology and Critical Care Medicine, Kyushu University Hospital Department of Critical Care Medicine, Kyushu University Hospital
  • Shono Yuji
    Emergency and Critical Care Center, Kyushu University Hospital
  • Tokuda Kentaro
    Department of Critical Care Medicine, Kyushu University Hospital
  • Akahoshi Tomohiko
    Emergency and Critical Care Center, Kyushu University Hospital
  • Yamaura Ken
    Department of Anesthesiology and Critical Care Medicine, Kyushu University Hospital Department of Critical Care Medicine, Kyushu University Hospital

Bibliographic Information

Other Title
  • ロラゼパム静注が診断と治療に有効だった悪性カタトニアの1症例

Search this article

Description

<p>Malignant catatonia is a syndrome characterized by psychomotor disorder with autonomic symptoms and hyperthermia. A 53-year-old woman with schizophrenia presented hyperthermia, immobility, mutism and rigidity, and was transported to our emergency room. After admission to the psychiatric ward, she developed respiratory failure. She was brought to the ICU and intensive care was initiated. After the exclusion of neuroleptic malignant syndrome and other physical diseases, we suspected malignant catatonia due to an exacerbation of schizophrenia. Thus, we administered lorazepam (1 mg, intravenously). Three minutes after the administration of lorazepam, her immobility, mutism and rigidity were ameliorated. When malignant catatonia is suspected, malignant catatonia should be differentially diagnosed from other physical diseases, while general care is provided to prevent complications. Then, a therapeutic diagnosis with lorazepam should be considered. Because lorazepam has a rapid onset, it is appropriate for the diagnosis and treatment of malignant catatonia.</p>

Journal

References(8)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top