上鼻甲介に発生したGlomangiopericytoma例

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  • A Case of Glomangiopericytoma of the Superior Nasal Turbinate
  • ジョウ ビ コウカイ ニ ハッセイ シタ Glomangiopericytomaレイ

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<p>Glomangiopericytoma (GAPC) is a type of hemangiopericytoma that develops in the sinonasal cavity; the first case was reported as a hemangiopericytoma in 1942. Based on the WHO classification of tumors, GAPC was independently defined in 2005, as a type of hemangiopericytoma originating from the sinonasal cavity. GAPC is rare among paranasal sinus tumors, accounting for approximately 0.5% of all paranasal tumors, and develops from the paranasal cavity in most cases. Herein, we report a case of GAPC that developed from the superior nasal turbinate. A 75-year-old woman visited our hospital with the chief complaint of snoring. Nasal endoscopy revealed a tumor mass in the olfactory cleft and a biopsy was obtained. The tumor was diagnosed as a GAPC from the histopathological and immunohistochemistry findings (vimentin-positive and alpha-SMA-positive). We performed endoscopic resection of the tumor, and no recurrence was observed for five years following the surgery. The histopathology provided a definitive diagnosis of GAPC. GAPC is generally a low-grade malignancy, but some case with high-grade malignancy have been reported. The latter cases require complete surgical removal. Endoscopic removal of the tumor is recommended as the first-line therapy. However, embolization and surgical incision should be considered in patients with large tumors and those in whom excessive bleeding from the tumor is expected. We did not undertake the above in our case, as the tumor was small and no excessive bleeding from the tumor was expected.</p>

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