Encephalitis/encephalopathy as neurological complications of COVID-19

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  • Nakajima Hideto
    Division of Neurology, Department of Medicine, Nihon University School of Medicine

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  • COVID-19による脳炎・脳症：SARS-CoV-2の神経向性について
  • COVID-19 ニ ヨル ノウエン ・ ノウショウ : SARS-CoV-2 ノ シンケイコウセイ ニ ツイテ

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<p>Coronavirus disease 2019 (COVID-19) mainly causes respiratory infections, however, there are increasing reports of neurological manifestations. I present here a comprehensive review of encephalitis/encephalopathy as neurological complications of COVID-19. The virus has been detected only scarcely in cerebrospinal fluid, there is accumulating evidence that CNS damage could be caused as para-infectious immune-mediated disease and neurological complications of the systemic effects of COVID-19, including acute disseminated encephalomyelitis and acute necrotizing encephalopathy. In COVID-19 cases with consciousness disturbance or psychological symptoms, it is necessary to evaluate clinical examination and therapeutic strategy on the assumption of the existence of encephalitis/encephalopathy associated COVID-19.</p>

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