Fluorescent and Bioluminescent Probes based on Precise Molecular Design
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- KUMADA Rei
- Department of Applied Chemistry, Keio University
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- ORIOKA Mariko
- Department of Applied Chemistry, Keio University
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- CITTERIO Daniel
- Department of Applied Chemistry, Keio University
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- HIRUTA Yuki
- Department of Applied Chemistry, Keio University
Bibliographic Information
- Other Title
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- 精密分子設計に基づく蛍光・生物発光プローブの開発と応用
- セイミツ ブンシ セッケイ ニ モトズク ケイコウ ・ セイブツ ハッコウ プローブ ノ カイハツ ト オウヨウ
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Abstract
<p>Fluorescence and bioluminescence have been actively applied to various chemical sensors and biosensors, including to cellular/in vivo imaging. On application to the detection of specific targets, it is necessary to develop fluorescent/bioluminescent probes that selectively respond to the target analytes such as molecules, ions or cells by changing their optical properties. The authors have focused on the development of small molecular probes by means of molecular design based on the desired function. In this paper, we describe the approaches to molecular design of fluorescent/bioluminescent probes and their applications, including the introduction of our recent research works. Finally, a future outlook for further functionalization of small molecular probes is provided.</p>
Journal
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- BUNSEKI KAGAKU
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BUNSEKI KAGAKU 70 (10.11), 601-616, 2021-10-05
The Japan Society for Analytical Chemistry
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Details 詳細情報について
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- CRID
- 1390290307610945792
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- NII Article ID
- 130008125739
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- NII Book ID
- AN00222633
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- NDL BIB ID
- 031797508
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- ISSN
- 05251931
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
- KAKEN
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- Abstract License Flag
- Disallowed