Effects of Glycosides on the Antioxidant Activity of Apigenin

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  • Apigeninの抗酸化活性に及ぼす配糖体の影響
  • Apigenin ノ コウサンカ カッセイ ニ オヨボス ハイトウタイ ノ エイキョウ

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type:P(論文)

The antioxidant effects of apigenin without glycoside (APG), apigenin 7-glucoside (APG-Glu) and apigenin 7-gentiobioside (APG-Glu-Glu) on phosphatidylcholine peroxidation were investigated using atomic force microscopy (AFM), and the effects of glycosides on the antioxidant activities of APG were discussed. The Langmuir-Blodgett film of 1-palmitoyl-2-linoleoyl-3-phosphatidylcholine (PLPC) was used as a model biological membrane for AFM. The AFM images clearly indicated that APG glycosides inhibited PLPC peroxidation and that the APG glycoside had a more potent antioxidant effect than APG without glycoside. It is suggested that the antioxidant effect on lipid peroxidation depends on the distribution and orientation of the antioxidant in the lipid membrane.

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